【摘 要】
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Objective To investigate the effects of DPP-4 inhibitor on β-cell function in patients with latent autoimmune diabetes in adults (LADA).Research design and methods Thirty newly diagnosed LADA patients
【机 构】
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Diabetes Center,Institute of Metabolism and Endocrinology,The Second Xiangya Hospital and Key Labora
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Objective To investigate the effects of DPP-4 inhibitor on β-cell function in patients with latent autoimmune diabetes in adults (LADA).Research design and methods Thirty newly diagnosed LADA patients were randomized 1:1 to receive insulin therapy with 100mg/day sitagliptin (group A) or without sitagliptin (group B) for 12 months.Fasting and 2-hour postprandial blood samples were obtained at baseline, 3, 6, 9 and 12 months of treatment to determine blood glucose, HbA1C and C-peptide levels.
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