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Eicosanoids are a group of oxygenated C20 polyunsaturated fatty acids.They mediate various insect physiological processes including reproduction, excretion, and immunity.Arachidonie acid (AA) is a main precursor of eicosanoid biosynthesis.Phospholipase A2 (PLA2) catalyzes AA release from phospholipids.Subsequent oxygenases of cyclooxygenase (COX) or lipoxygenase (LOX) transform AA to prostaglandins (PGs) or leukotrienes (LTs).