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  5. Shift from the reaction system of paraoxonase 1 to the peroxidation reaction system of myeloperoxida

Shift from the reaction system of paraoxonase 1 to the peroxidation reaction system of myeloperoxida

来源 :第十二届中国介入心脏病学大会(CIT2014) | 被引量 : 0次 | 上传用户：xl122700059
【摘 要】
：
Background HDL,paraoxonase 1 (PON1) and myeloperoxidase (MPO) form a functional ternary complex,which is involved in oxidative stress and atherosclerosis.The triangular relation among HDL,PON1 and MPO
【作 者】
：
Wang Fan Liu Yawen Cong Yetong Li Pengpeng Li Yong Tang Yuan Yan Zhihui Cheng Yi Zheng Yang 
【机 构】
：
Cardiovascular Center,the First Hospital of Jilin University,Changchun,Jilin,China Department of Epi
【出 处】
：
第十二届中国介入心脏病学大会(CIT2014)
【发表日期】
：
2014年3期
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论文部分内容阅读
Background HDL,paraoxonase 1 (PON1) and myeloperoxidase (MPO) form a functional ternary complex,which is involved in oxidative stress and atherosclerosis.The triangular relation among HDL,PON1 and MPO forms the scenario of oxidative stress and cholesterol regulation.The aim of study was to assess the interconnectivity between the peroxidation reaction system of MPO (MPO peroxidation activity and H2O2;PRSM) and reaction system of PON1 (PON1 activity and Ca2+;RSP1) and oxidative stress and cholesterol regulation in healthy participants and atherosclerotic patients with normal cholesterol levels.
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