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  5. COMBODY: One-Domain Antibody Multimer with Improved Avidity

COMBODY: One-Domain Antibody Multimer with Improved Avidity

来源 :2011第三届中国北京抗体大会 | 被引量 : 0次 | 上传用户：wooicheang
【摘 要】
：
The smallest possible antigen binding domain has been built into a multimer molecule, dubbed as Combody, by fusing to a coiled-coil structure derived from cartilage oligomeric matrix protein.Combody h
【作 者】
：
Bin Gao 
【机 构】
：
The Centre for Molecular Immunology Institute of Microbiology Chinese Academy of Sciences China
【出 处】
：
2011第三届中国北京抗体大会
【发表日期】
：
2011年1期
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　　The smallest possible antigen binding domain has been built into a multimer molecule, dubbed as Combody, by fusing to a coiled-coil structure derived from cartilage oligomeric matrix protein.Combody has high avidity to its antigen and can be multiple specific and possibly, has improved pharmacokinetics.
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