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  5. Nitroso-ene Enabled Construction of 1,3-Benzodiazepine Derivatives

Nitroso-ene Enabled Construction of 1,3-Benzodiazepine Derivatives

来源 :中国化学会第十六届全国有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户：qiaoweizhuo
【摘 要】
：
The legendary of Sternbach orchestrates an era of benzodiazepine heterocycles in the history of drug development.In the last five decades,benzodiazepine(1)has been evolved as a privileged platform in
【作 者】
：
Chao Wang Yin Liu Zhuwei Ruan Lili Zhu Sha-Hua Huang Ran Hong 
【机 构】
：
CAS Key Laboratory of Synthetic Chemistry of Natural Substances,Center for Excellence in Molecular S
【出 处】
：
中国化学会第十六届全国有机合成化学学术研讨会
【发表日期】
：
2019年3期
【关键词】
：
benzodiazepinone copper cyclization hydroxamic acid nitroso-ene 
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　　The legendary of Sternbach orchestrates an era of benzodiazepine heterocycles in the history of drug development.In the last five decades,benzodiazepine(1)has been evolved as a privileged platform in drug discovery for the treatment of anxiety,fear,or phobia in the field of central nervous system(CNS)by binding to GABA receptors[1].
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