2. 您的位置
3. 首页
4. 会议论文
5. Epitope Mapping of Antibodies against Neurotoxin and Cardiotoxin Ⅲ by Hydrogen/Deuterium Exchange Ma

Epitope Mapping of Antibodies against Neurotoxin and Cardiotoxin Ⅲ by Hydrogen/Deuterium Exchange Ma

来源 :2018年中国质谱学术大会 | 被引量 : 0次 | 上传用户：hbjysd520

【摘 要】

：

Epitope mapping has been considered a powerful tool that can elucidate binding mechanism and largely facilitates the development of vaccines and drugs.

【作 者】

：

Wei-Ya Chen Wang-Chou Sung Sung-Fang Chen 

【机 构】

：

Department of Chemistry,National Taiwan Normal University,Taipei,Taiwan

【出 处】

：

2018年中国质谱学术大会

【发表日期】

：

2018年7期

【关键词】

：

Epitope mapping snake venom toxins HDX LC-MS 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Epitope mapping has been considered a powerful tool that can elucidate binding mechanism and largely facilitates the development of vaccines and drugs.

其他文献

Balanced Dual Emissions from Tridentate Phosphine-Coordinate Copper(Ⅰ)Complexes toward HighlyEfficie

It is known that the excited-state structural distortion of Cu(Ⅰ) complexes is one of the main nonradiative channels,rendering EL efficiency reduction,[1] which can be suppressed through fixing molecu

会议

Theoretical Study on the Reaction Mechanism of β-Chloride Elimination from Square-Planar Nickel Comp

The β-chloride elimination or β-hydrogen elimination usually undergoes a ligand dissociation process(Scheme 1,Path A) in an organometallic textbook.

会议

Chemoselective Reduction of Cyclic imides with Hydrosilanes:Tuning the Selectivity with Catalysts an

The reduction of cyclic imides gives several nitrogen containing products which are important structure motifs in natural products and pharmaceuticals and versatile building blocks for organic synthes

会议

Application of Iminophenyl Oxazolinylphenylamine in Highly Enantioselective Cobalt-catalyzed Hydrosi

Design of chiral privileged ligands is one of the most challenging and efficient strategies for asymmetric transformations.

会议

铑催化下3-重氮吲哚-2-亚胺与1,3-丁二烯的[4+3]环加成反应

α-重氮羰基化合物和α-重氮亚胺作为金属卡宾的前体在有机合成中具有广泛的应用[1].我们课题组新近发展了一类具有吲哚骨架的环状α-重氮脒类化合物,即3-重氮吲哚-2-亚胺,它们作为一类新的金属卡宾前体,能够发生[2+1]环加成(即环丙烷化)、[3+2]环加成、C-H 插入、N-H 插入及相关串联反应,生成结构多样的含吲哚骨架的杂环化合物[2].

会议

Dehydrogenative Cross-Coupling Reaction Between N-Aryl α-Amino Acid Esters and Phenols or Phenol Der

A novel dehydrogenative cross-coupling(DCC) reaction between N-aryl glycine esters and phenols or 1,3,5-trimethoxybenzene was developed by copper catalysis using di-tert-butyl peroxide DTBP as an oxid

会议

A Cascade C-H Functionalization/Amidation Reaction for Synthesis of Azepinone Derivatives

A cascade C-H functionalization/amidation reaction of aminobiaryls 1 with diazomalonates 2 has been developed under rhodium catalysis.

会议

Divergent and Stereoselective Synthesis of β-Silyl-α-Amino Acids via Pd-Catalyzed Intermolecular Sil

α-Amino acids(α-AAs) are the important building blocks of bioactive peptides,peptidomimetics and proteins.

会议

Nickel-catalyzed ortho-halogenation of unactivated(hetero)aryl C-H bonds with lithium halides using

Recently,the cost-attractive nickel salts have been identified as powerful catalysts for the transformation of unactivated C-H bonds into C-C,C-N,C-O or C-S bonds.

会议

Characterization of co-existing protein conformers and dynamic assembly of protein machineries using

Characterization of structure and dynamics of various protein states is important for understanding molecular mechanisms of processes including assembly of protein machineries,protein denaturation,agg

会议

hydrogen/deuterium exchange (HDX)capillary electrophoresis (CE)stopped-flowto