Cystathionine β-synthase and cystathionine γ-lyase regulate VEGF and sFlt-1 production in human plac

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  Imbalance release of proangiogenic and antiangiogenic factor from placenta causes maternal endothelial dysfunction,the main manifestation of preeclampsia (PE).Recently,hydrogen sulfide (H2S) has been shown to have a pro-angiogenic effect and human placenta is able to produce H2S.
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