9-Azido analogs of three sialic acid forms for metabolic remodeling of cell-surface sialoglycans

来源 :第二届糖合成化学青年学术研讨会 | 被引量 : 0次 | 上传用户：cn1976

【摘要】

：

　　Neu5Ac,Neu5Gc and KDN are three basic forms of sialic acids in vertebrates.We reported the synthesis and metabolic incorporation of the 9-azido analogs of t

【作者】

：

Bo Cheng Lu Dong Yuntao Zhu Rongbing Huang Yuting Sun Xing Chen

【机构】

：

SyntheticandFunctionalBiomoleculesCenter,BeijingNationalLaboratoryforMolecularSciences,CollegeofChem

【出处】

：

第二届糖合成化学青年学术研讨会

【发表日期】

：

2017年5期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Neu5Ac,Neu5Gc and KDN are three basic forms of sialic acids in vertebrates.We reported the synthesis and metabolic incorporation of the 9-azido analogs of three sialic acid forms in mammalian cells.

其他文献

多价糖肽抗肿瘤疫苗的合成与评价

随着癌症免疫疗法的兴起,旨在增强患者自身免疫系统以清除肿瘤细胞的抗肿瘤疫苗具有广大应用前景.肿瘤相关MUC1 糖肽被认为是癌症最重要的抗原靶标.然而,由于多肽表位的免疫

会议

O糖基化生产细菌多糖-蛋白结合疫苗

会议

糖基化生产细菌多糖

三种抗坏血酸糖苷的合成及其α-糖苷酶抑制活性

2-O-β-D-葡萄糖基-L-抗坏血酸(AA-2βG)是从枸杞中分离得到的一种天然抗坏血酸糖苷化合物,本文通过化学方法合成了AA-2βG 及其两种类似物(AA-2βGal 和AA-3βG),并用商品化

会议

Microbial Biosynthesis of Glycosaminoglycans and Its Oligomers

Glycosaminoglycans and its oligomers have been widely used in the fields of cosmetic,functional food and medicine.Here,by applying the strategies of synthetic b

会议

以NKT细胞激动剂为内嵌佐剂的抗肿瘤糖疫苗

如何打破免疫系统对肿瘤糖抗原的免疫耐受,引发高滴度的IgG 抗体是抗肿瘤糖疫苗的研究难点之一.NKT 细胞具有独特的免疫作用模式:在没有辅助T 细胞参与的情况下,NKT 细胞能帮

会议

苯乙醇苷类天然产物的发散性合成

天然苯乙醇苷是一类以取代苯乙醇为苷元的糖类化合物,它们存在于多种药用植物中,并具有重要的生物活性,如抗氧化活性、神经保护活性、抗肿瘤活性及保肝活性等[1],因此它们自

会议

Detection Method of Chromium Based on Anthraquinone Fluorescent Probes

Anthraquinone compounds have many medicinal properties,such as anti-tumor,pharmacological and immunological activities.In addition,they are also important dye.

会议

Evidence of Robust Participation by equatorial 4-O group in glycosylation on a 2-Azido-2-deoxy-gluco

　　Neighboring group participation by 2-O-carboxylate esters is of fundamental importance to carbohydrate chemistry and thus the sective introduction of 1,2-tr

会议

N-glycosylation inhibitor tunicamycin suppresses the self-renewal of glioma-initiating cell

　　Glioma-initiating cells possess tumor-initiating potential and are relatively resistant to conventional chemotherapy and irradiation.Therefore,their elimina

会议

Diversity-Oriented Synthesis of Deoxysugars:Preparation of All Eight Stereoisomers of 2,3,6-Trideoxy

会议

SynthesisAll

9-Azido analogs of three sialic acid forms for metabolic remodeling of cell-surface sialoglycans

与本文相关的学术论文