Colorectal cancer (CRC) is currently the fourth most common cause of cancer death worldwide.Approximately 50% of patients develop distant metastases in the liver, which is the most common site; approximately 25% of patients exhibit synchronous metastases at the time of diagnosis.Although CRC-related deaths have decreased in the western world over the past few years, a twofold to fourfold increase in the incidence of CRC has been observed in Asian countries of China, Japan, Korea, and Singapore over the last two decades.With various ethnic, epidemiological,and genetic differences, strategies should be developed to manage CRC in Asia.Thus, the Network of Colorectal Cancer Multi-Disciplinary Teams in Asia Pacific Region (NECTAR)was established in 2011.The NECTAR initiative aims to build an excellent Asian network of centers that share common frameworks, protocols, and treatment goals based on evidence and best practice approach in the management of metastatic colorectal cancer (mCRC).The NECTAR group consists of members from29 centers from nine Asian countries, which form the NECTAR Council, who meets periodically to discuss and formulate activities and initiatives; such activities aim to attain the objectives established by a group of experts.