Six1 Homeoprotein Suppresses Human Colorectal Cancer Cells Growth by Inhibiting Wnt/-catenin Signali

来源 :2011第四届世界癌症大会 | 被引量 : 0次 | 上传用户:fengjintao1111
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Colorectal cancer (CRC) has become one of the leading causes of cancer-related deaths in Hong Kong.The overactive Wnt/β-catenin signaling may contribute to colorectal carcinogenesis by promoting proliferation, preventing apoptosis and enhancing the motile and invasive capabilities of tumor cells.Six 1, a nuclear homeodomain protein essential for the development of diverse tissues, has a close and complex association with Wnt/β-catenin signaling in various biological processes.
其他文献
  Hepatoeellular carcinoma (HCC) is a devastating disease whcre worldwide incidence and mortality are broadly similar, emphasizing its lethality.Most HCCs occ
会议
1、固体废弃物再利用与循环经济固体废物是指人类在生产建设、日常生活和其他活动中产生的,在一定时间和地点无法利用而被丢弃的固体、半固体物质。在我国固体废弃物处理要遵
  Pathologists are the "Diagnostic Oncologists" who are becoming increasingly involved in cancer management decision making.The progressive reliance on non-su
会议
  With the recent advances in the knowledge of hepato-carcinogenesis, there has been encouraging development in the targeted therapy of advanced hepatocellula
会议
"只记书本上没有的东西"1921年春天,爱因斯坦同妻子一起到美国组织募捐,为犹太族青年创办一所大学筹集资金。当时有许多美国人来见他,并提一些问题:你可记得声音的速度是多少?你如何记才
在日本研修一年回国后,对于冬季我国儿童的衣着服饰别有一番感慨。特别是再碰上一个低温天气,就更不得了。孩子们虽然被家长捂得严严的,但是还避免不了伤风、感冒,给家长和
  Chemoradiation is the mainstay of treatment management for locally advanced cervical cancer.Delivery of treatment to these advanced cervical cancers can be
会议
钢筋混凝土偏心受压构件应用非常广泛,如钢筋混凝土拱桥的主拱圈、刚架桥的支柱、桥墩、隧洞衬砌以及厂房中支承吊车梁的柱等一般多为偏心受压构件。 根据截面上受力情况的
  PERP (p53 apoptosis effector related to PMP-22) is an apoptosis-specific effector of the major tumour suppressor p53.Down-regulation of PERP, both at transc
会议
  Colorectal cancer is the second leading cause of death from cancer in the developed countries.Although great efforts have been made to early diagnosis a rel
会议