【摘 要】
:
Background: Patients underwent hematopoietic stem cell transplantation (HSCT) experience rapid bone loss after HSCT.The magnitude of fractures and the risk factors remain unknown.
【机 构】
:
University of Texas MD Anderson Cancer Center, Houston Texas, USA
【出 处】
:
第七届国际骨质疏松及骨矿盐疾病学术会议
论文部分内容阅读
Background: Patients underwent hematopoietic stem cell transplantation (HSCT) experience rapid bone loss after HSCT.The magnitude of fractures and the risk factors remain unknown.
其他文献
Background: Calcitriol (1,25(OH)2D3), a powerful regulator of phosphate metabolism and immune response, is generated by 25-hydroxyvitamin D 1 o-hydroxylase (1 α H) in the kidney and in macrophages.Ren
Background: Bone mineral density (BMD), a diagnostic parameter for osteoporosis and a clinical predictor of fracture,is a highly heritable trait, but the genetic variants involved are largely unknown.
Background: Neurotrophic factors have been implicated in bone fracture healing.Recently, we observed the most prominent induction ofneurotrophin-3 (NT-3) among all members of the neurotrophin family d
Background: Hypophosphatemic rickets (HR) is a disorder of phosphate homeostasis characterized by rachitic, growth retardation, hypophosphatemia and renal phosphate wasting.X-linked dominant HR (XLHR)
Background: Osteoporosis is a typical complexdisease diagnosed by the measurement of bone mineral density (BMD), which is a highly heritable and multifactorial trait.Previous studies have demonstrated
Arthritis, including rheumatoid arthritis and osteoarthritis,is a chronic, painful and disabling disease affecting millions of people worldwide.Murine models of arthritis are an important tool for bot
Background: Dysregulated miRNAs in osteoclasts caused osteoclasts dysfunction contributing to skeletal disorders and modulating dysregulated miRNA in osteoclasts could regulate their dysfunction.But t
Background: Metabolic skeletal disorders associated with impaired bone formation (e.g., osteoporosis) are still major clinical challenges.RNAi provides a promising approach to address the challenges.H
Background: Lung cancer is the major cause of malignancyrelated death worldwide.Metastases account for 90% of lung cancer deaths, and frequently target the skeleton and lead to rapid deterioration in
Background: Annulus fibrosus (AF) regeneration is critical to intervertebral disc repair, yet remains challenging due to the remarkable heterogeneity of AF tissue.Since the stiffness of substrate dete