Outstanding smallness is,of course,remarkable characteristic of the extended-nano (EN) fluidic channels.However,the ultimate smallness brings out unique properties of liquid and fluid in EN channels.They are dominated by the surface and interface surrounding EN space.We have utilized these characteristics to novel analytical and energy devices,and also,we are now elucidating the unique properties of EN space.The first topics are the utilization of smallness.At least in our research group,micro fluidic devices have gone into practical phase.In contrast to micro fluidics,EN fluidics is still in launching stage.The size region of 101-102 nm,that is EN space,is still unexplored area.We fabricated EN channels into glass microchips,and succeeded in fluidic control and chemical processing such as chromatographic separation.EN-channels are connected to micro channels,and these micro channels are substantial size interface between EN and macro worlds.The most important breakthroughs are detection and low temperature glass bonding methods.Our differential interference contrast thermal lens microscope,DIC-TLM,enabled ultrasensitive detection and determination of non-fluorescent molecules in EN space which is even shorter than optical wavelength.The low temperature glass bonding enabled surface modification (functionalization) before bonding,and we could introduce variety of surface modification into EN channels.We applied the EN fluidic devices to pico-litter immunoassay and atto-litter chromatography.Pico to femto litter is much smaller than the volume of a living cell,and therefore,single cell single molecule analysis with keeping the cell alive will be available.The atto-litter chromatography will be introduced in this talk.The unique properties of EN fluid are mainly brought by surface.Viscosity,dielectric constant,proton mobility,conductivity,and other properties change in EN space.The causes of them are revealing to be attributed to the behavior of proton which is provided by surface group.These unique properties have been applied to novel energy devices.Self hydrogen supplying fuel cell will be introduced as an example.