黄芪多糖对人胃癌细胞系MGC-803的生长抑制作用及细胞周期的影响

来源 :江苏省药理学会第六届学术研讨会 | 被引量 : 0次 | 上传用户：woaini009

【摘要】

：

目的:通过不同浓度、不同时间的黄芪多糖作用于人胃癌细胞系MGC-803,探讨其对胃癌细胞的生长抑制作用及细胞周期的影响.方法:用RPMI 1640培养液对人胃癌细胞MGC-803进行传代培养,采用MTT法检测黄芪多糖对MGC-803的生长抑制作用,采用流式细胞术检测黄芪多糖对MGC-803细胞周期的影响.结果:MTT法实验显示黄芪多糖可抑制MGC-803细胞增殖；细胞周期分析提示黄芪多糖可将细胞M

【作者】

：

王琼朱萱萱周杰王海丹倪文澎符蕊

【机构】

：

南京中医药大学附属医院,南京210029 南京中医药大学

【出处】

：

江苏省药理学会第六届学术研讨会

【发表日期】

：

2012年12期

【关键词】

：

胃癌黄芪多糖药理机制细胞增殖周期波动

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Beneficial effects of dihydromyricetin on hydrogen peroxide-induced injury and apoptosis of vascular

Aim:To study the beneficial effects of dihydromyricetin (DMY) on hydrogen peroxide-induced (H2O2) injury and apoptosis of vascular smooth muscle cells (VSMCs).Methods:VSMCs were seperated from rat aor

会议

Effects of Ganoderma Lucidum Polysaccharids on Expression of NF-κB and Inflammatory Factors in Ather

Qbjectives Observing the effects of ganoderma lucidum polysaccharids on NF-κB and inflammatory factors in atherosclerosis rats,to study the possible mechanism of ganoderma lucidum polysaccharids on at

会议

p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autoph

The present study sought to investigate mechanisms by which p53 induction contributes to excitotoxic neuronal injury.Rats were intrastriatally administered the N-methyl-d-aspartate (NMDA) receptor ago

会议

autophagyDRAMexcitotoxicityLC3NF-κB

The Effect of miRNAs on angiogenesis-dependent Cancer

Angiogenesis,the process of blood vessel formation,has been deemed the "common denominator" shared by diseases and conditions that harm about a billion people globally.From AIDs to Alzheimers,blood ve

会议

Akebia Saponin D attenuates amyloid β-induced cognitive deficits and inflammatory response:involveme

Neuroinflammatory responses caused by amyloid β(Aβ) play an important role in the pathogenesis of Alzheimers disease (AD).Aβ is known to be directly responsible for the activation of glial cells and i

会议

Alzheimer's diseaseAkebia saponin D (ASD)Amyloid β(Aβ)1-42Cognitive impa

NG, a novel PABA/NO-based oleanolic acid derivative, induces human hepatoma cell apoptosis via a ROS

NG,a novel PABA/NO-based derivative of oleanolic acid (OA),has been found to show potent antitumor activity both in vivo and in vitro.In the present study,NG could significantly reduce tumor volume an

会议

Hepatocellular carcinomaNitric oxideOleanolic acidApoptosisReactive oxygen s

PPARγ agonist pioglitazone reverses memory impairment and biochemical changes in a mouse model of ty

会议

pioglitazonecognitionβ-amyloidBACE1NF-κBdiabetes mellitus

1H NMR-based Metabolomics Exploring Biomarkers in Rats Cerebralspinal Fluid After Cerebral Ischemia/

In our study,metabolomics was used to investigate biochemical changes in the early stages of rats focal cerebral ischemia reperfusion(I/R) injury.Cerebrospinal fluid (CSF) samples of 0,0.5,1,3,and 6h

会议

metabolomics1H NMRcerebrospinal fluidrat brain ischemic/reperfusion injury

黄精多糖对脂多糖(LPS)诱导人脐静脉内皮细胞(HUVEC)损伤的保护机制研究

目的:探讨黄精多糖对LPS诱导HUVEC损伤的保护作用.方法:采用HUVEC为研究对象,MTT法检测黄精多糖对LPS诱导HUVEC损伤的影响,Hoechst33258荧光染色法检测黄精多糖抗凋亡的作用效果.结果:黄精多糖与HUVEC共培养后没有引起细胞活力的明显改变,排除了实验中药物的直接细胞毒作用,通过MTT法可以发现,黄精多糖可以显著减少LPS与HUVEC共培养后,LPS对HUVEC造成的损伤

会议

脐静脉内皮细胞损伤脂多糖黄精多糖分子机制

Effect of Astragalus Polysaccharides on Chronic Atrophic Gastritis induced by N-methyl-N′-nitro-N-ni

Objective To investigate the effect and the mechanisms of astragalus polysaccharides (APS) on chronic atrophic gastritis (CAG) induced by MNNG in rats.Method Seventy rats were randomly divided into si

会议

CAGAPSEGFRMMP-2cox-2/PGE2

黄芪多糖对人胃癌细胞系MGC-803的生长抑制作用及细胞周期的影响

与本文相关的学术论文