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  5. A panel of monoclonal antibodies for tree shrew regulatory T cells

A panel of monoclonal antibodies for tree shrew regulatory T cells

来源 :首届昆明灵长类动物模型学术论坛 | 被引量 : 0次 | 上传用户：sjhung888
【摘 要】
：
Regulatory T (Treg) cells are now generally recognized to play a pivotal role in immune functions and diseases.However,no antibodies are available for studies i
【作 者】
：
Chao Wang Wen-Ju Wang Ming-Li Li 
【机 构】
：
KeyLaboratoryofAnimalModelsandHumanDiseaseMechanismsoftheChineseAcademyofSciences,YunnanProvince,Kun
【出 处】
：
首届昆明灵长类动物模型学术论坛
【发表日期】
：
2012年11期
【关键词】
：
Tree shrew Regulatory T cells Monoclonal antibodies 
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论文部分内容阅读
Regulatory T (Treg) cells are now generally recognized to play a pivotal role in immune functions and diseases.However,no antibodies are available for studies in tree shrews.We have first cloned the full-length coding genes for the surface markers and functional molecules of tree shrew Tregs [CD3 (ε chain),CD4,CD25,CD127,CTLA-4 and PD-1] and then successfully generated a full panel of monoclonal antibodies against them.
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