目的 This study aims to compare NOX T3 study at-home to in-lab polysomnogram and simultaneous NOX T3 study.Secondly,we aim to compare the diagnostic accuracy of the NOX T3 portable sleep monitor to that of simultaneously recorded in-lab polysomnogram(PSG)in adults being evaluated for obstructive sleep apnea(OSA).方法 A total of 81 participants were recruited following face-to-face evaluation at PKU Peoples hospitals sleep center.All participants initially performed an overnight HST using the Nox-T3 portable monitor.Within 2 weeks of the HST,participants performed an in-laboratory PSG with a simultaneous Nox-T3 portable monitor recording.PSG records were manually scored using the American Academy of Sleep Medicine(AASM)criteria,and PM records were double-scored using the devices autoscore algorithm as well as manual scoring.Two separate manually edited scorings were performed using different definitions for hypopnea in both HST and PSG,1)events with ≥ 30％reduction in airflow from baseline for ≥ 10 seconds accompanied by ≥ 4％oxygen desaturation,and 2)events with ≥ 30％reduction in airflow from baseline for ≥ 10 seconds associated with ≥ 3％reduction in oxygen saturation and/(or an arousal in PSG).The ability of subjects to perform HST was assessed as the percentage of successful HST on first and second recording attempts and HST quality.结果 The final sample consisted of 81 participants(63 males,18 females)with a mean±SD age,ESS,BMI,of 47.65±13.98,10.28±5.11,27.55±5.45Kg/m2.Successful rate for 1st HST and 2nd NOX study in lab was 93.75％(75/80),95％(76/80).No one failed in second times home study when the first time of HST failed.And average apnea- hypopnea index ±SD(AHI 3％oxygen desaturation for hypopnea)in 1st NOX,2nd NOX and PSG was 28.54±20.35/h,32.54±22.39/h,33.51±23.2/h.Manual score-derived T3 AHI(3％)and PSG-derived AHI(3％)were strongly related(r =.92).The T3(manual scored AHI)demonstrated a high degree of sensitivity for the presence of obstructive sleep apnea syndrome(OSA； 100％)and high specificity for the diagnosis of OSA when AHI ≥5 events/h(93.15％).The unit(manual scored)had a high degree of both sensitivity(95.83％)and specificity(83.3％)when the presence of OSA was defined more conservatively(AHI ＞ 15 events/h).The unit(manual scored)had a high degree of both sensitivity(97.56％)and specificity(86.49％)when the presence of severe OSA was defined as AHI ＞ 30 events/h.结论 In this clinic-based sample,this type Ⅲ portable monitor demonstrated to be easy for patients to complete the HST.And it is very good measurement agreement compared to PSG and a high degree of sensitivity and specificity for detecting OSA including mild,moderate and severe OSA.