A preliminary study on the efficacy of sequential injection therapy of glucocorticoid and hyaluronan

来源 :第十五届上海地区医用生物材料学术研讨会 | 被引量 : 0次 | 上传用户:fujilee
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Objective: To investigate the efficacy of sequential injection therapy of glucocorticoid and hyaluronan for knee osteoarthritis.Methods: From August 2012 to August 2013, 64 patients (27 males and 37 females) with knee osteoarthritis were treated in our hospital department.
其他文献
Objective: Repair of large segmental bone defects is one of the challenging problems in orthopaedic surgery.Our previous studies demonstrated that bioactive borate glass (BG) has good osteoinductivity
会议
Objective: Recently, accumulating evidences have shown that exosomes, a key component of cell paracrine secretion, can exert therapeutic effects in various disease models, such as tissue ischemia and
会议
Objective: In situ forming hydrogel have attracted attention for bone defect repair.Among the various fabrication methods (such as two-components or thermo-responsive one-component gelation), photopol
会议
目的:世界卫生组织统计显示全世界平均每年的注射次数为120亿次,其中5%用于免疫接种.因此迫切需要一种快速、简便的免疫接种途径,无针传递方式尤其是透皮免疫的出现为实现该目标提供了可能.醇质体是一种定向的药物载体,属于靶向给药系统的一种新剂型,具有低毒性、低免疫性、良好的细胞相容性等优点,因而在透皮免疫的研究领域受到广泛关注.本实验基于醇质体制备和层层自组装技术,将抗原装载在醇质体里并在醇质体外通过
Introduction: Scaffold plays important role in tissue engineering, which can provide a 3D environment for cells growth and guide tissue regeneration.In recent years, nanofibrous scaffold began to be f
目的:近年来,水凝胶由于具有良好的生物可降解性,广泛应用于生物材料的研究中。葡聚糖是一种细菌多糖,其分子长链上分布着大量的羟基,经过氧化,羟基变成醛基后具备较强的化学活性,可以与其他表面带有官能团的物质进行反应,以提高材料的稳定性和生物利用度。壳聚糖能够模拟由多糖类和糖胺聚糖构成的细胞外基质。本研究用氧化后的葡聚糖与壳聚糖进行化学交联,制备一种可用于负载生长因子的生物材料。方法:将一定量的高碘酸钠
Objective: Gene therapy has been considered as a promisingapproach for diseases treatment and has drawngreat attention over the past decades.However, theprospects for the application of PEI are negati
目的:水凝胶作为一种具有三维网络交联的亲水聚合物,能维持水分而不溶解于水中,柔软而又富有弹性,类似于生物组织,且具有很好的生物相容性和优良的生物降解性.近年来,基于天然材料的水凝胶在组织工程中受到广泛的关注.但是由于天然高聚物水凝胶具有较差的力学性能而限制了其在组织工程中的应用,因此本实验通过在天然水凝胶制备过程中引入介孔二氧化硅纳米粒子(MSNs),研究二氧化硅的加入量来对水凝胶机械性能的影响.
目的:通过有限元分析的方法评价3D打印钛合金骨盆假体的生物力学性能.方法:选取1例男性右侧髂骨巨大软骨肉瘤患者,拟行半骨盆切除人工半骨盆置换术.术前行CT和MRI检查,利用三维图像融合技术判断髂骨周围肿瘤侵袭范围,确定外科边缘及截骨平面,根据截骨后骨盆缺损范围利用计算机辅助设计(CAD)建立患者骨盆有限元模型,经过有限元分析后利用3D打印技术定制个性化钛合金骨盆假体.在Abaqus软件中对已建立的
Objective: To evaluate the biomechanical properties of a titanium alloy pelvic prosthesis individually manufactured by 3D printing through finite element analysis.Methods: A male patient with a huge c