From Genotype to Phenotype A Five-track Stratification to Address the Complexity of Life

来源 :2016年第三届全国功能基因组学学术峰会 | 被引量 : 0次 | 上传用户:kevingod1981
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Associating genotype to phenotype at molecular level is always a challenge.In "the Informational (Genetic) World" all relationships are described in DNA sequence and its terms for genotypes so that the solution is by definition partial.It is now overwhelmingly replaced by "the Dynamic World" and to solve the life equations that assume two unknowns – genetics and epigenetics – is of urgency.In such real biological world,our first effort concerns convergence that focuses on the unification of concepts and terms from four clusters of disciplines,including (1) medicine (such as physiology and anatomy),(2) molecular biology (such as cell biology and biochemistry),(3) genetics (such as population genetics and molecular evolution),and (4) genomics (such as systems biology and bioinformatics).
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