【摘 要】
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Objectives Adriamycin (ADR) has broad-spectrum effect such as anti-tumour and antibiotic, but it is limited the application for its dose-dependent cardiac toxicity.PICK1 is the interaction protein of
【机 构】
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Department of Pharmacology,Hubei University of Science and Technology,Xianning 437100,China;Hubei Pr
【出 处】
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第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int
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Objectives Adriamycin (ADR) has broad-spectrum effect such as anti-tumour and antibiotic, but it is limited the application for its dose-dependent cardiac toxicity.PICK1 is the interaction protein of PKC, which has been suggested as a potential drug target against brain ischaemia, pain and cocaine addiction.Our previous study has shown that the expression of PICK1 has increased in ADR-induced toxic myocarditis.
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