【摘 要】
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The characterization of the landscape of genetic lesions that underlie cancer has been significantly advanced with the recent application of next-generation sequencing (NGS) technology.To define the g
【机 构】
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Department of Computational Biology St.Jude Children's Research Hospital Memphis, TN
【出 处】
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Genome Variation in Precision Medicine(第四届《自然遗传》疾病基因组学国际研讨会)
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The characterization of the landscape of genetic lesions that underlie cancer has been significantly advanced with the recent application of next-generation sequencing (NGS) technology.To define the genomic landscapes of 21 different pediatric cancer subtypes of brain tumors, solid tumors and leukemias, we analyzed > 1,000 pediatric cancers and matched control tissue by whole-genome, whole-exome or RNASeq as part of the St Jude Childrens Research Hospital-Washington University Pediatric Cancer Genome Project (PCGP).
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