• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. MeRIP-PF: An Easy-to-use Pipeline for High-resolution Peak-finding in MeRIP-Seq Data

MeRIP-PF: An Easy-to-use Pipeline for High-resolution Peak-finding in MeRIP-Seq Data

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户：ttingting
【摘 要】
：
Background: RNA modifications, especially methylation of the N6 position of adenosine (A)--m6A, represent an emerging research frontier in RNA biology.With the rapid development of high-throughput seq
【作 者】
：
李语丽 田东梅 宋述慧 
【机 构】
：
所级中心生物信息部,中国科学院北京基因组研究所,北京,100101;中科院大学,北京,100049
【出 处】
：
第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会
【发表日期】
：
2014年4期
【关键词】
：
RNA modifications m6A MeRIP-Seq peak calling 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　Background: RNA modifications, especially methylation of the N6 position of adenosine (A)--m6A, represent an emerging research frontier in RNA biology.With the rapid development of high-throughput sequencing technology, in-depth study of m6A distribution and function relevance becomes feasible.
其他文献
Integrating copy number variation and gene expression to study the synergic effects of miRNA and TF
Background: Pairs of gene expression profiling and CNV profiling in same cancer samples can help to identify expression signatures associated with CNV.In these studies, the relationship between CNV an
会议
Copy number variationDosage effectmiRNA and TFOvarian cancerthree-dimensiona
Compendium of Protein Lysine Modifications: from acetylation, ubiquitination to new modifications
Background: Recently, lysine was discovered as a hot spot amino acid for the protein post-translation modifications.Besides relatively well-studied protein lysine modifications (PLMs) such as methylat
会议
protein lysine modificationdatabasecrosstalk
A multicell model for enhancer prediction based on AdaBoost algorithm and shape features of chromati
Background: Accurate identification of DNA regulatory elements has become an urgent need in the post-genomic era.Recently, a number of machine learning-based approaches have been developed to predict
会议
Enhancer predictionnon-coding genome annotationgene regulationmachine learnin
Phosphoproteome Comparative Analysis of Naked Pupa and Normal Silk Quantity Strain in Bombyx mori
Background: Silkworm is the typical model organism of Lepidoptera.As its gene experission in silk gland owns timeliness and spatiality, the increasing number of researchers devote to using it as the b
会议
Silkworm Bombyx moriPhosphoproteomeSilk Quantity
Translational Selection is More Pronounced in Human Housekeeping Genes
Background: Translational selection is a ubiquitous and significant mechanism to regulate protein expression in prokaryotes and unicellular eukaryotes.Recent evidence has shown that translational sele
会议
translational selectioncodon usage biasexpression regulationhousekeeping gene
Patterns of nucleosome occupancy around transcription factor binding sites in human cells
Background: Transcription factor (TF) binding at specific DNA sequences is the fundamental step in transcriptional regulation, and is highly dependent on the local chromatin structure context in eukar
会议
nucleosometranscription factor binding siteclustering
ThermoMatch: genome-wide oligonucleotide binding sites prediction based on thermodynamics
Determination of oligonucleotide binding sites is crucial for nucleotide hybridization based molecular biological technology, such as PCR.Although sequence similarity method such as BLAST was adopted
会议
ThermodynamicsThermoMatchBLASTPCR
Study on the Relationships between Histone Modifications and Gene Expression Levels in the Human H1
Background: It is well known that histone modifications can control gene expression, and the data of histone modifications have grown exponentially by the next-generation sequencing techniques.Based o
会议
histone modificationgene expressionregional distributionembryonic stem cells
Asymmetric Evolution of Human Transcription Factor Regulatory Networks
Background: Changes in cis or trans regulatory regions are the major driving forces that underlie the evolution of gene expression.Transcription factors (TFs) are the main trans factors involved in tr
会议
transcription factorgene duplicationregulatory divergenceENCODE
A regulatory network of divergently expressed genes induced by phorbol myristate acetate (PMA) and h
Background: It is critical to study the mechanisms of erythroid and megakaryocytic differentiation for developing therapeutic strategies for blood disease.Although previous studies provided numerous e
会议
divergently expressed geneserythroid differentiationmegakaryocytic differentia