活化素A对骨肉瘤细胞增殖、侵袭和迁移的影响

来源 :中华医学会第十七届骨科学术会议暨第十届COA国际学术大会 | 被引量 : 0次 | 上传用户：kaiyuanwu

【摘要】

：

目的探讨活化素A在骨肉瘤细胞中的表达变化，并探讨活化素A对骨肉瘤细胞生物学行为的影响及其可能机制，以便为骨肉瘤的预后判断以及靶向治疗等提供科学依据.方法培养骨肉瘤细胞系(MG63、SaOS-2和U2OS)和正常人成骨细胞系(hFOB1.19)，采用Trizol试剂和RIPA裂解液分别提取细胞的总RNA和总蛋白，通过实时荧光定量PCR和western blotting技术分别分析活化素A mRN

【作者】

：

朱建炜刘璠

【机构】

：

南通大学附属医院骨科

【出处】

：

中华医学会第十七届骨科学术会议暨第十届COA国际学术大会

【发表日期】

：

2015年4期

【关键词】

：

骨肉瘤活化素A 增殖转移

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活化素A对骨肉瘤细胞增殖、侵袭和迁移的影响

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