Data-independent acquisition(DIA)based quantitative proteomics,such as SWATH-MS,has emerged to be a critical technique,which enables highly consistent quant
1 Background 3 steps in protein identification:Translatomics(Ribosome profiling,Ribo-seq) we propose a novel strategy and develop a software system called IPomi
Protein-protein interactions(PPIs)are fundamental to protein structure and function.Perturbations of PPIs can cause deleterious effects on cellular activiti
Protein identification and quantification are basic steps in proteomics study.This presentation will focus on our recent progress in the development of soft
Onco-proteogenomics research was focused on the discovery of driver mutations.The detection of single amino-acid variants(SAVs)usually depends on single-nuc
In comparison to other biofluid and tissue samples,urine has some unique advantages that make it a suitable source for disease biomarker discovery.Firstly,u
Metabolomics:From sample to clinic Application of metabolomics in clinic Procedures of metabolomincs study Preanalytical aspects:collection,operation,transporta
Chemical isotope labeling strategy is widely applied in the proteolytic peptides-based “Bottom-up” proteomic strategy and thousands of proteins could be f
Cell-cell interactions are often mediated by protein molecules expressed by one cell that are recognized by specific receptors present on neighboring cells.