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Twenty-four,6-month-old goats were divided into four groups of six animals.Three groups were vaccinated with 1 x1014 phage particles of clone 1,2,and 3,with adjuvant at the beginning and 4 weeks later.Group 4 (control) were immunized with phage M13KE.All groups were challenged with 200 metacercariae of F.hepatica at week 6 and sacrificed at week 20.