【摘 要】
：
DNA is unarguably the carrier of genetic information.However, DNA sequence alone cannot explain how hundreds of cell types in a complex multi-cellular organ
【机 构】
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InstituteofBiophysics,ChineseAcademyofSciences
【出 处】
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第十一次全国基因功能与表观遗传调控学术研讨会
论文部分内容阅读
DNA is unarguably the carrier of genetic information.However, DNA sequence alone cannot explain how hundreds of cell types in a complex multi-cellular organism, such as a human individual can possess distinct transcription programs, while sharing the same genetic information.This is believed to be achieved by fine-tuning our genetic information with a so-called "epigenetic" system.To fulfill the two basic tasks challenging the multi-cellular organisms, epigenetic system must simultaneously offer dual characteristics, "Plasticity & Inheritability".Plasticity allows the transformation of one genome into hundreds of epigenomes and transcriptomes, whereas inheritability permits the maintenance of every single epigenome and its corresponding transcriptome.
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