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Particulate matter (PM2.5) is an important risk factor for asthma.Recent study showedautophagy is associated with asthma pathogenesis.However, the exact mechanisms underlyingPM2.5-induced autophagy in asthma are poorly understood.In this work, we evaluatedthe PM2.5-induced autophagy in Beas-2B cells and analyzed the possible molecularmechanism.