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保留部分近端前列腺部尿道的腹腔镜前列腺癌根治术:附31例报告
【机 构】
：
浙江大学医学院附属邵逸夫医院,杭州
【出 处】
：
泌尿生殖肿瘤华夏医学论坛2016暨长城国际泌尿男科转化医学论坛2016
【发表日期】
：
2016年8期
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从1989年作者成为硕博连读研究生，开展泌尿系统肿瘤基因研究至今已经整整26年了。作者在多位老师的悉心指导下，应用PCR及第二代测序技术，先后在小儿Wilms瘤、肾癌及膀胱癌等泌尿生殖系统肿瘤开展单基因、多基因及多组学研究；发现膀胱癌21个高频突变基因和8个染色质重塑基因，后者被Cell评论创立癌症发生的“染色质重塑-肿瘤抑制理论”；发现肾癌进化及转移新机制；发现膀胱癌突变频率最高的Driver基
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泌尿系肿瘤是泌尿外科最常见的疾病之一，目前在泌尿系肿瘤相关疾病的诊断与治疗方面存在很多争议。我们利用循证医学的方法比较这些疾病不同诊治方案的差异，为泌尿系肿瘤的临床诊治方案选择提供更加可信的依据。
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