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5. An Iridium(Ⅲ)-based Inhibitor of BRD4 with Potent Anticancer Activity in vivo

An Iridium(Ⅲ)-based Inhibitor of BRD4 with Potent Anticancer Activity in vivo

来源 :2016第九届世界癌症大会 | 被引量 : 0次 | 上传用户：linebarrel2

【摘 要】

：

Bromodomain-containing protein 4 (BRD4) has recently emerged as an attractive epigenetic target for anticancer therapy.In this study,an iridium(Ⅲ) complex is reported as the first metal-based inhibito

【作 者】

：

Hui-Min David Wang 

【机 构】

：

Department of Fragrance and Cosmetic Science Graduate Institute of Natural Products Kaohsiung Medica

【出 处】

：

2016第九届世界癌症大会

【发表日期】

：

2016年7期

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　　Bromodomain-containing protein 4 (BRD4) has recently emerged as an attractive epigenetic target for anticancer therapy.In this study,an iridium(Ⅲ) complex is reported as the first metal-based inhibitor of BRD4.

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