IL-1 receptor accessory protein as a surface marker for leukemia stem cells is related to clinical p

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户:doer
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Chronic myeloid leukemia (CML) is a clonal disease from hematopoietic stem cells.Surviving leukemia stem cells (LSCs) and progenitor cells are a potential source for CML relapse and progression.Recent data reported that IL-1 receptor accessory protein (IL1RAP) gene was differentially expressed in CML versus normal stem and progenitor cells.However,whether the level of IL1RAP is associated with clinical phases of CML,and correlations between IL1RAP expression and detections of diagnosis is still unclear.
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