MiR-222 modulate multidrug resistance in human colorectal carcinoma by down-regulating ADAM-17

来源 :2013医学前沿论坛暨第十三届全国肿瘤药理与化疗学术会议 | 被引量 : 0次 | 上传用户:woshishen654123
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Object Colorectal carcinoma is a frequent cause of cancer-related death in men and women.miRNAs (microRNAs) are endogenous small non-coding RNAs that regulate gene expression negatively at post-transcriptional level.In the present study we investigated the possible role of microRNAs in the development of MDR (multidrug resistance) in colorectal carcinoma cells.
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