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5. Planning Sample Size Using MMRM in Confirmatory Trials

Planning Sample Size Using MMRM in Confirmatory Trials

来源 :上海交通大学 | 被引量 : 0次 | 上传用户：qq12433184000

【摘 要】

：

When planning sample size in confirmatory trials,the sample size is estimated from hypothesized effect size of the underlying study treatment.In order to account for potential dropout during the study

【作 者】

：

Tao Song 

【机 构】

：

Biostatistics Spectrum Pharmaceuticals Inc,Irvine,CA,92618,USA

【出 处】

：

上海交通大学

【发表日期】

：

2016年4期

【关键词】

：

MMRM sample size study design missing data 

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　　When planning sample size in confirmatory trials,the sample size is estimated from hypothesized effect size of the underlying study treatment.In order to account for potential dropout during the study,it is not uncommon to ignore the data for subjects who drop out of the study before the primary endpoint is reached.

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