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Aim:Canosic acid is a phenolic diterpene,which is considered to be the most important antioxidant constituent of Rosemarinus officinalis L and Salvia officinalis L.But carnosic acid is almost insoluble in water.The absorption of CA is slow after intragastric administration.The absolute bioavailability of camosic acid is low.Therefore,to improve the oral b ioavailability of carnosic acid,the camosic acid self-emulsified delivery system was prepared and evaluated.