Control of the Synthesis of Cholesterol

来源 :The 2016 International Conference on Lipid Metabolism and Bi | 被引量 : 0次 | 上传用户:dxcnet2009
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  If cholesterol is not balanced,it is detrimental to human health.However,how cholesterol synthesis is controlled beyond HMGCR,the target of the statins,is poorly understood.7-dehydrocholesterol reductase (DHCR7) is the terminal enzyme of cholesterol synthesis in the Kandutsch-Russell pathway,converting 7-dehydrocholesterol (7DHC) to cholesterol.
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