Leflunomide Inhibition of proliferation and apoptosis of human cytomegalovirus infection in human em

来源 :中华医学生物免疫学会第二届学术年会 | 被引量 : 0次 | 上传用户:liongliong500
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  Objective To explore the mechanism of Leflunomide(LEF) protecting human embryonic lung fibroblast injury,to provide the theory in LEF antiviral function to human cytomegalovirus (HCMV).Methods Control group,HCMV group,GCV+HCMV group,and LEF+HCMV group.Control group,containing 0.02% DMSO in RPMI 1640 culture medium,HCMV stimulation in cell culture medium by adding HCMV,GCV +HCMV treated group both in cell culture medium added GCV and HCMV,LEF+HCMV treated group both in cell culture medium added LEF and HCMV,after 24h,48h and 72h and cell morphology was observed perturbation.
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