【摘 要】
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It has been shown that G-rich DNA can fold into G-quadruplex with a variety of monovalent and divalent metal cations.Here we measured the spectral characteristics and thermostability of the G-quadrupl
【出 处】
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中国物理学会2011年秋季学术会议
论文部分内容阅读
It has been shown that G-rich DNA can fold into G-quadruplex with a variety of monovalent and divalent metal cations.Here we measured the spectral characteristics and thermostability of the G-quadruplexes of TBA in the presence of Pb2+ using a combination of CD and UV.CD spectra illustrated that G-rich segments of DNA could form a special structure with a strong signal at 312 nm.Analysis of the titration data reveals saturate Pb2+/TBA binding stoichiometry was 1∶1.
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