【摘 要】
：
We have synthesized certain 6-substituted 9-methoxy-11H-indeno[1,2-c]quinolin-11-ones for antiproliferative evaluation.Results indicated that 6-alkylamine derivatives,6-[2-(dimethylamino)ethylamino]-9
【机 构】
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Department of Medicinal and Applied Chemistry,College of Life Science,Kaohsiung Medical University,K
【出 处】
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第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会
论文部分内容阅读
We have synthesized certain 6-substituted 9-methoxy-11H-indeno[1,2-c]quinolin-11-ones for antiproliferative evaluation.Results indicated that 6-alkylamine derivatives,6-[2-(dimethylamino)ethylamino]-9-methoxy-11H-indeno [1,2-c]quinolin-11-one(5a)and its 6-[3-(dimethylamino)propylamino] derivative,5b,were able to inhibit cells growth completely at a concentration of 100 μM.
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