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目的:研究雅连和味连对内毒素所致小鼠死亡率的影响。方法:采用小鼠尾静脉注射脂多糖的方法,连续48h观察小鼠死亡情况。结果:味连小剂量组能明显延长小鼠受脂多糖攻击后的存活时间(P<0.01),雅连小剂量组和味连小剂量组均能降低脂多糖致小鼠死亡率,与模型组相比,差异有统计学意义(P<0.01,P<0.001)。结论:味连小剂量能够明显延长内毒素小鼠的生存时间,降低死亡率,其作用优于雅连。
Objective: To study the effects of Ya-Lian and Wei Lian on endotoxin-induced mouse mortality. Methods: The mice were injected intravenously with lipopolysaccharide (LPS) for 48 hours to observe the death of mice. Results: The Xiaolian low-dose group could prolong the survival time of mice treated with lipopolysaccharide (P <0.01), the Ya-Lian low-dose group and Xiaolian low-dose group could reduce the mortality of mice induced by lipopolysaccharide, Group, the difference was statistically significant (P <0.01, P <0.001). Conclusion: Xiaolian low dose can significantly prolong the survival time of endotoxin mice and reduce mortality, its effect is better than Ya Lian.