【摘 要】
：
Objective:Qiliqiangxin(QL),a traditional Chinese medicine,had long been used to treat chronic heart failure.Recent studies revealed that differentiation of cardiac fibroblasts(CFs)into myofibroblasts
论文部分内容阅读
Objective:Qiliqiangxin(QL),a traditional Chinese medicine,had long been used to treat chronic heart failure.Recent studies revealed that differentiation of cardiac fibroblasts(CFs)into myofibroblasts played an important role in cardiac remodelling and development of heart failure,however,little was known about the underlying mechanism and whether QL treatment being involved.
其他文献
目的：络病理论作为传统中医药的重要组成部分，取得了重大进展和突破，首次创立了“理论-临床-新药-实验-循证”学术发展新模式，建立“络病证治”理论体系，构建“脉络学说”和营卫“由络以通、交会生化”理论，开辟通络治疗临床难治性疾病新途径，理论和临床研究促进创新专利中药研发，并开展实验研究揭示其作用机制，循证评价临床疗效，为中医药转化医学发展提供了典范。
目的：观察复方中药通心络对脑缺血大鼠微血管的影响.方法：将48只健康SPF级SD大鼠随机分为六组：假手术组、模型组、通心络大剂量组(1.6g/kg？d)、通心络中剂量组(0.8g/kg？d)、通心络小剂量组(0.4g/kg？d)、尼莫地平组(10mg/kg？d)，每组8只.采用开颅结扎法阻断大鼠一侧大脑中动脉制作局灶性脑缺血大鼠模型，假手术组大鼠只挑开脑膜，不结扎血管.
目的：目的探讨原发性高血压(EH)患者颈动脉粥样硬化斑块及性质与血浆纤维蛋白原(Fib)的关系。方法入选454例EH患者，根据是否合并颈动脉硬化斑块，分为EH伴斑块组(n=235)，与EH无斑块组(n=169)，对二组受试者血浆纤维蛋白原水平及斑块性质进行比较，并运用多因素回归对颈动脉粥样硬化斑块与血压、血脂、血糖、Fib水平进行分析。
Objective:A traditional Chinese medicine,Qiliqiangxin(QLQX)has been identified to perform protective effects on myocardium energy metabolism in mice with acute myocardial infarction,though the effects
Objective:Tongxinluo(TXL)is a compound prescription formulated according to the meridian theory of traditional Chinese medicine.It may play an important role in cardiovascular protection by improving
Objective:Qiliqiangxin(QL)has been used for the treatment of chronic heart failure in China.Accumulating evidence suggests QLs cardioprotective effects on continuous myocardial ischemia.However,it is
Objective:In a multicenter randomized double-blind study we demonstrated that Qiliqiangxin(QLQX),a traditional Chinese medicine,had a protective effect in heart failure patients.However,whether and vi
Objective:It has been reported that Qiliqiangxin(QL),a traditional Chinese medicine compound,could inhibit cardiac hypertrophy and remodeling,and improve cardiac function.However,whether and how it re
Objective:Tongxinluo(TXL)has been shown to decrease myocardial necrosis after ischemia/reperfusion(I/R)by simulating ischemia preconditioning(IPC).
Objective:In contrast to cardiomyocytes,autophagy in cardiac microvascular endothelial cells(CMECs)during ischemia/reperfusion(I/R)injury has not been fully investigated.Tongxinluo(TXL),a traditional