Here we report an improvement in nanoparticle design to enhance drug accumulation and penetration at tumor site.We prepare a series of bovine serum albumin-poly(N-3-acrylamidophenylboronic acid)nanopa
The cancer drug delivery process is a cascade of five steps consisting of circulation in blood,accumulation and penetration into the tumor,cellular internalization and intracellular drug release,or th
Superparamagnetic nanoparticles have received great attention owing to their potential applications as contrast agents for magnetic resonance imaging(MRI).
Fluorescence-based techniques are inherently sensitive,selective,convenient,diverse and non-destructive,and also can provide real time,in situ and analyses,thereby; they have been widely used in biolo
In the past decade,degradable polymeric nanocarriers such as micelles,polymersomes and nanoparticles have emerged as one of the most promising platforms for targeted cancer chemotherapy.
We have previously demonstrated that cationic lipid-assisted polymer nanoparticles with stealthy property can successfully deliver nucleic acids to tumor cells,and the efficient delivery of siRNA in v