PRETREATMENT OF ADSCS WITH EXENDIN-4 IMPROVE THERAPEUTIC EFFICIENCY FOLLOWING MYOCARDIAL INFARCTION

来源 :第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int | 被引量 : 0次 | 上传用户：lyx_suda

【摘要】

：

【作者】

：

Liu Jianfeng Chen Yundai

【机构】

：

Department of Cardiology,Chinese PLA General Hospital,Beijing,China

【出处】

：

第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int

【发表日期】

：

2013年2期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Objectives Exendin-4 has the strong anti-oxidant andanti-inflammatory properties.Reactive oxygen species (ROS) produced in ischaemic niche play a pivotal role in stem cells detachment from the impairedmyocardium.To improve the poor retention and survival of transplanted stemcells in infarcted myocardium,we tested the hypothesis that pretreatment of adipose-derived stem cells (ADSCs) with Exendin-4 can improve the therapeuticefficacy of ADSCs by enhancing the adhesion.

其他文献

CREG PROMOTES VASCULOGENESIS OF EMBRYONIC STEM CELLS BY ACTIVATING PI3K/AKTNEGF PATHWAY

Objectives Vasculogenesis plays an important role under both physiological and pathological conditions.Factors controlling vasculogenesis is still far to be fully elucidated.

会议

ASSOCIATION BETWEEN POLYMORPHISM IN THE CHEMOKINE CCL21 GENE RS10972201 AND CORONARY ARTERY DISEASE

Objectives Atherosclerosis is an inflammatory disease characterised by the formation of atherosclerotic plaques.Homeostatic chemokine CCL21 was up-regulated within the atherosclerotic lesions, which c

会议

EFFECT OF ATORVASTATIN ON ENDOTHELIUM-INDEPENDENT RELAXATION OF SMALL PULMONARY ARTERIES IN MONOCROT

Objectives To examine the preventive effect of atorvastatin on sodium nitroprusside (SNP)-induced endothelium-independent relaxation (EDiR) in small pulmonary artery (SPA) rings in monocrotaline (MCT)

会议

THE STUDY ABOUT INFLUENCE OF CD147 KNOCKDOWN ON ATHEROSCLEROTIC PLAQUE STABILITY

Objectives To observe the effects of CD147 on matrix metalloproteinase 9 (MMP 9) expression and secretion in aortic atherosclerotic plaque in rabbits, and explore the function of CD147 knockdown to pr

会议

MUTATION SPECTRUM IN A LARGE COHORT OF UNRELATED CHINESE PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY

Objectives Hypertrophic cardiomyopathy (HC) is a hereditary heterogeneous cardiovascular disorder.Data published to date was mainly in Caucasians and large study is needed in Chinese population.We wer

会议

INVOLVEMENT OF RETINOL BINDING PROTEIN 4 IN INSULIN-INDUCED VASCULAR SMOOTH MUSCLE CELL PROLIFERATIO

Objectives Retinol binding protein 4 (RBP4)-a newly discovered adipocytokines, has been found to be associated with obesity,insulin resistance, cardiac vascular disease (CVD), metabolic syndrome close

会议

ENDOPLASMIC RETICULUM STRESS IS INVOLVED IN ADVANCED GLYCOSYLATION END PRODUCTS-INDUCED CARDIOMYOCYT

Objectives To investigate the effect of endoplasmic reticulum stress (ERS) in the process of advanced glycosylation end products (AGEs)-induced neonatal rat cardiomyocyte apoptosis.Methods Cultured ne

会议

ENDOPLASMIC RETICULUM STRESS IS INVOLVED IN ADVANCED GLYCOSYLATION END PRODUCTS-INDUCED CARDIOMYOCYT

会议

A RYR2-V1810L MUTATION IDENTIFIED IN A CHINESE PATIENT WITH CLINIC MANIFESTATION OF POSTURAL ORTHOST

Objectives Postural orthostatic tachycardia syndrome (POTS) is an autonomic disorder characterised by an increase heart rate,syncope and an elevated plasma norepinephrine in response to posture change

会议

THE EFFECT OF INTERMEDIN ON ANGIOTENSIN Ⅱ AND ENDOTHELIN-1 INDUCED VENTRICULAR MYOCYTE HYPERTROPHY I

Intermedin (IMD) is a novel peptide related to calcitonin gene-related peptide (CGRP) and adrenomedullin (ADM), which may have localised actions as a modulator of cardiac function.The aim of the study

会议

PRETREATMENT OF ADSCS WITH EXENDIN-4 IMPROVE THERAPEUTIC EFFICIENCY FOLLOWING MYOCARDIAL INFARCTION

与本文相关的学术论文