The prognostic and predictive value of carbohydrate antigen 19-9 in metastatic colorectal cancer pat

来源 :第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会 | 被引量 : 0次 | 上传用户:ccc_tw
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Objective: We had previously demonstrated that the carbohydrate antigen 19-9(CA19-9),lactate dehydrogenase(LDH),neutrophil lymphocyte ratio(NLR)are prognostic factors for patients with metastatic colorectal cancer(mCRC).In this study,we try to analysis the association of these blood-based biomarkers with bevacizumab efficacy in the first line setting.
其他文献
Background: Clinical trials have revealed a important but not consistent association between programmed death ligand-1(PD-L1)expression and response to checkpoint blockade therapy.How to define a thre
Background and Aims: An increasing number of research has revealed that the immune microenvironment of hepatocellular carcinoma(HCC)is associated with tumor development.Lots of inflammatory factors ar
Background: Gastric cancer(GC)is the fourth most common malignant disease worldwide and the second most common cause of death from cancer.Most patients are initially diagnosed with unresectable,locall
Background:The ability of the 2010 World Health Organization(WHO)grading system,and American Joint Committee on Cancer(AJCC)staging system to stratify patients with gastric neuroendocrine tumors(g-NET
Background: Kras activation and p16 inactivation are required for development of pancreatic ductal adenocarcinoma(PDAC).However,the biochemical mechanisms underlying these double alterations remain un
Myeloid Deprived Suppressor Cell(MDSC)has been raised to be a novel target for multiple cancers.However,target agents on MDSC has not displayed promising efficacy.One of the critical reasons shall be
目的 构建人结肠癌裸鼠皮下移植瘤模型、经脾注射肝转移模型及盲肠原位移植瘤模型.方法 将人结肠癌细胞(HCT-116)接种于裸鼠皮下及脾被膜下,分别构建皮下移植瘤模型和经脾注射肝转移模型;以裸鼠皮下肿瘤为瘤源,将其剪切后移植于另一组裸鼠盲肠浆膜下,构建原位移植瘤模型.[结果]皮下移植瘤模型均有成瘤,但未见到局部侵袭、淋巴转移及血行转移等现象;经脾肝转移模型建模6 周后脾脏成瘤率为100%(6/6),
Oxaliplatin(OX)and 5-fluorouracil(5-FU)are two chemotherapeutic agents for colon cancer.However,the chemoresistance to such conventional therapeutic agents still remains a major challenge in cancer tr
会议
Background: Tumor vessels supported by pericytes were considered to be responsible for the failure of some anti-angiogenic agents.It remains undefined when it comes to bevacizumab.We tried to analysis
Background: To optimize the high b values(>200s/mm2)for intravoxel incoherent motion imaging of rectal cancer and to observe the effect of high b values variation on IVIM parameters.Methods:Twenty two
会议