【摘 要】
：
Protein tyrosine phosphatase(PTP) 1B is a potential therapeutic target for type 2 diabetes.Due to the positively charged nature of its catalytic site,PTP1B is an intractable target for drug discovery
【机 构】
：
Institute of MateriaMedica,Chinese Academy of Medical Sciences
【出 处】
：
第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会
论文部分内容阅读
Protein tyrosine phosphatase(PTP) 1B is a potential therapeutic target for type 2 diabetes.Due to the positively charged nature of its catalytic site,PTP1B is an intractable target for drug discovery and the achievement of in vivo activity is one of the major bottlenecks.
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