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<正>Idiopathic pulmonary fibrosis(IPF),featured as the vast accumulation of ECM in the lung interstitum,is a chronic and lethal human disease with few treatment options.IPF patients have a median survival of approximately2-3 years after diagnosis due to an irreversible loss of lung function and respiratory failure.Since fibrillar collagens are major components of fibrotic lung matrices,understanding how fibroblasts or myofibroblasts receive and