The technique of Robotic Nano manipulation extends peoples ability into nano scale,which generates a significant influence to the modern science.It provides new feasible ways to solve the problems that traditional technique cannot achieve.In this talk,we will present the demonstration of nanorobot for its applications in biological study firstly.Then aiming at meeting the new function requisites aroused from the multidiscipline research,we introduce the recent progress of nanorobot in perspective of system integration.The integration here includes two meanings.One is developing technologies based on nanorobot itself,such as more accurate manipulation,fast scanning,molecular recognition and so on.Another meaning is creating new functions through integrating other advanced techniques into nanorobot system,such as planar patch clamp,Scanning Ion Conductance Microscopy,Optical-induced tweezers.Each new integrated technology generates a boarder impact to the applications of nanorobot.The examples show the problems that cannot be investigated with traditional method can be elucidated through the work of nanorobot based integration,which in turn shows nanorobot as system integration leads to an improved significance and scientific value.