【摘 要】
:
To develop effective mucosal vaccines,two types of functional liposomes,the mannosylated lipid A-liposomes (MLLs) with a size of around 200 nm and the stealth lipid A-liposomes (SLLs) of 50 nm,both lo
【机 构】
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School of Biological and medical Engineering,Hefei University of Technology,Hefei 230009,China
【出 处】
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Fourth Symposium on Innovative Polymers for Controlled Deliv
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To develop effective mucosal vaccines,two types of functional liposomes,the mannosylated lipid A-liposomes (MLLs) with a size of around 200 nm and the stealth lipid A-liposomes (SLLs) of 50 nm,both loaded with a model antigen ovalbumin and ammonium bicarbonate (NH4HCO3),were prepared and fabricated together into microneedles to form the proSLL/MLL-constituted microneedle arrays (proSMMAs) which anhydrous and stable and,upon rehydration,dissolved rapidly,recovering the initial MLLs and SLLs[1,2].
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