【摘 要】
:
Aims Our study aimed to investigate the protective effects of Holothurian intestines (HI) on nonsteroidal anti-inflammatory drugs (NSAIDs) induced gastric mucosal damage in rats.Materials and methods
【机 构】
:
Department of Infectious Diseases, Affiliated Hospital of Qingdao University
【出 处】
:
The 14th Congress of Gastroenterology China(第十四届全国消化系病学术会议)
论文部分内容阅读
Aims Our study aimed to investigate the protective effects of Holothurian intestines (HI) on nonsteroidal anti-inflammatory drugs (NSAIDs) induced gastric mucosal damage in rats.Materials and methods Gastric lesions on 60 male wistar rats were induced with indomethacin (IDM, 30mg/kg).The rats were pretreated for 15 consecutive days with saline, sucralfate, and HI in different doses (0.4 g/kg, 0.8 g/kg and 1.6 g/kg, respectively).Fasting for 24 h, the animals were administered with IDM; after 6 hours,killed.
其他文献
Objective To evaluate the continuous endoscopic sclerotherapy for eliminating efficacy and complications of esophageal varices.Methods From October 2009 to October 2013, the second hospital of Shanxi
Background andaims Hepatitis Bvims X protein (HBx) isinvolved in the pathogenesis of hepatocellular carcinoma (HCC).Increased expression of transcripts from P3 and P4 promoters of the insulinlike grow
Aim This study aimed to investigate the prevalence and significance of ultrasound-detected deep abdominal lymphadenopathy in autoimmune liver disease.Try to find a new method of differential diagnosis
Objective The aim of this study was to examine the antitumor effect of Shikonin, including proliferation, apoptosis, invasion and metastasis, and to explain the possible molecular mechanisms involved.
Background and objective Macrophages play an important role in pathogenesis of IBD.Toll-like receptor 4 (TLR4) activated macrophages to secrete plenty of cytokines which regulated inflammation and imm
Aims Capsule endoscopy (CE) is useful in diagnosis of intestinal lymphagiectasia (IL).However, systemic analysis of endoscopic and clinical characteristics remains unavailable.Methods Review the endos
Objective Acute pancreatitis (AP) is a rare condition in pregnancy and prompts urgent hospitalization.We investigated the etiology, features of clinical manifestation, the strategy of management and i
Background As the lack of reliable treatment for irritable bowel syndrome prompts interest in the development of new therapies,we aimed to systematically evaluate the effect of Lactobacillus in treati
Objective To investigate the possibility of HMCB1-A box specific inhibition HMGB1/TLR signaling pathway, to provide theoretical and experimental evidence for HMGB 1-A box is to target treatment IBD.Me
Aim Endoscopic Submucosal Dissection (ESD) is performed increasingly recently, meanwhile aritificial ulcer after ESD has been paid more and more attention.We aimed to systematically evaluate the evide