Discovery of Aquaporin-3 as a sperm protein essential for postcopulatory sperm osmoadaptation

来源 :中国细胞生物学学会全体会员代表大会暨第十二次学术大会 | 被引量 : 0次 | 上传用户:gaolei000
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  In the journey from the male to female reproductive tract, mammalian sperm experience a natural osmotic decrease (e.g., in mouse, from ~41 5 mOsm in the cauda epididymis to ~310 mOsm in the uterine cavity).At one hand, the hypotonic stress upon ejaculation is beneficial for mouse sperm motility "start-up" (evolutionary trait from fish sperm); However, the hypotonic stress could also cause potential harms to sperm function by inducing un-wanted cell swelling.
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