Estrogen receptor (ERα) up-regulated the transcriptional activity of the MDR1 gene in ER-positive br

来源 :中华医学会第十四次全国妇科肿瘤学术会议 | 被引量 : 0次 | 上传用户:liusha5188
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Breast cancer is one of the most common malignant tumors in women, accompanying with high rate of morbidity and metastasis.Drug resistance is a major block for successful chemotherapy of breast cancer.Over-expression of ATP-binding cassette super-family transporters that function as pumps to extrude anticancer drugs from cancer cells has been well known to be closely related to drug resistance phenotype.
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