孕酮通过上调妊娠相关血浆蛋白A的表达促进滋养层细胞的黏附与增殖

来源 :2014年全国糖生物学学术会议 | 被引量 : 0次 | 上传用户：tzwizj

【摘要】

：

胚胎发育和着床是一个复杂的生理过程,同时也是建立及维持妊娠的重要步骤.孕酮在调节胚胎与子宫内膜黏附及胚胎细胞增殖过程中发挥重要的作用.研究表明:妊娠相关血浆蛋白A (pregnancy-associated plasma protein A,PAPPA)是一种由胚胎分泌的糖蛋白,血清中PAPPA的水平从孕早期开始增加,但是关于孕酮和PAPPA相互作用关系及PAPPA对胚胎细胞的黏附和增殖的影响尚无

【作者】

：

王娇刘帅秦华民赵越王晓琦燕秋

【机构】

：

大连医科大学生物化学与分子生物学教研室,辽宁省糖生物学重点实验室,辽宁大连,116044 大连医科

【出处】

：

2014年全国糖生物学学术会议

【发表日期】

：

2014年8期

【关键词】

：

黏附胚胎 PAPPA 孕酮细胞增殖

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孕酮通过上调妊娠相关血浆蛋白A的表达促进滋养层细胞的黏附与增殖

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