Novel Phenylthiazole Derivatives as Potential Orthosteric FFA2 Agonists

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：xiaohw123456

【摘要】

：

Free fatty acid receptor 2(FFA2),also known as GPR43,is activated by short-chain fatty acids(SCFAs)which are mainly produced by the gut microbiota through the fermentation of undigested carbohydrates

【作者】

：

Taijin Wang Heying Pei Liang Ma

【机构】

：

Kidney Research Institute,West China Hospital of Sichuan University,Chengdu 610041

【出处】

：

2015年全国药物化学学术会议暨第五届中英药物化学学术会议

【发表日期】

：

2015年3期

【关键词】

：

FFA2 agonist SCFA Phenylthiazole derivatives Flexible docking

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　　Free fatty acid receptor 2(FFA2),also known as GPR43,is activated by short-chain fatty acids(SCFAs)which are mainly produced by the gut microbiota through the fermentation of undigested carbohydrates and dietary fibers.

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Novel Phenylthiazole Derivatives as Potential Orthosteric FFA2 Agonists

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