2. 您的位置
3. 首页
4. 会议论文
5. Pathophysiology of early-onset generalized DYT1 dystonia

Pathophysiology of early-onset generalized DYT1 dystonia

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：ztt399

【摘 要】

：

DYT1 early-onset generalized torsion dystonia is an inherited movement disorder associated with mutations in DYT1 that codes for torsinA protein.

【作 者】

：

Yuqing Li Fumiaki Yokoi Hong Xin Mark DeAndrade Lin Zhang Chad Cheetham David Lovinger Mai Dang 

【机 构】

：

Department of Neurology,College of Medicine,University of Florida,Gainesville,32610,USA

【出 处】

：

The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

dystonia dopamine LTP LTD torsinA motor skill basal ganglia 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　DYT1 early-onset generalized torsion dystonia is an inherited movement disorder associated with mutations in DYT1 that codes for torsinA protein.

其他文献

The endpoint of antidepressant treatment in social defeat stress mice associated with BNDF expressio

Objective At the preclinical level,the social defeat paradigmis considered one of the most robust models of stress-induced mood-related illnesses which possesses higher face,predictive,and ethological

会议

depressionsocial defeat stressduloxetinefluoxetineBDNF

Otx1 promotes basal dendritic growth and regulates intrinsic electrophysiological and synaptic prope

The transcription factor Otx1 is specifically expressed in layer V pyramidal cells(L5PCs)in the cerebral cortex.

会议

basal dendritesburst firing patternconnecting probabilityexcitatory postsynap

Finding the neural correlates of visual perceptual learning:a neural network approach

会议

Direct and indirect modes of functional control of DRN serotonergic neurons

The dorsal raphe nucleus(DRN)contains the largest group of forebrain-projecting serotonergic neurons which are involved in various biological processes including stress,reward and food intake.

会议

serotonindorsal raphe nucleusGABAinputmonosynapticexcitation-inhibition

Role of 5-HT1B receptors in hippocampal CA1 on learning and memory

Objective: The CA1 region of the hippocampus has been demonstrated as key brain zone in learning and memory.The direct entorhinal projection(temporoammonic,TA)input to hippocampal area CA1 was involve

会议

learning and memoryhippocampusSerotonin 1B receptor (5-HT1B R)kalirin-7

Control of social dominance by dorsal medial prefrontal cortex

会议

To explore the role of vestibular factors in spatial orientation among normal adults

Vestibular afferent information is important clue for spatial orientation(SO).In the case of aviation,marine,microgravity and vestibular lesions,individuals may experience spatial disorientation(SD)be

会议

spatial orientationvestibular systemspatial disorientationspatial cognitionv

Regulation of cortical seizure by optical stimulation of reticular thalamic nucleus

Seizure is a common neurological disorder which affects 1%of population worldwide.

会议

epilepsyoptogeneticreticular thalamic nucleusGABA antagonistthalamocortical

De novo GRIN2A mutation results in early-onset epileptic encephalopathy:from molecular mechanism to

Objective N-methyl-D-aspartate(NMDA)receptors play important role in neurological diseases,including epilepsy.

会议

NMDA receptorepilepsychannelopathy

Optogenetic control of thalamus as a tool for interrupting penicillin induced seizures

Objective Penicillin epilepsy model,whose discharge resembles that of human absence epilepsy,is one of the most useful acute experimental epilepsy models.

会议

optogeneticsepilepsypenicillin